Fig. 5
From: Mechanistic study of lncRNA UCA1 promoting growth and cisplatin resistance in lung adenocarcinoma
UCA1 enhanced the cisplatin resistance ability of LUAD cell lines. A UCA1-overexpressing A549 cells were more resistant to cisplatin, with higher IC50. B UCA1-knockdown A549/DDP cells were more sensitive to cisplatin, with lower IC50. C Western blot analysis of ERCC1 protein showed that UCA1 could enhance the cisplatin resistance of A549 cells. D UCA1 knockdown reduced the protein expression level of ERCC1. *P < 0.05, **P < 0.01, ***P < 0.001