Fig. 7
From: Mechanistic study of lncRNA UCA1 promoting growth and cisplatin resistance in lung adenocarcinoma
Knockdown with UCA1 restored cisplatin sensitivity of cisplatin-resistant cell lines in vivo. A Two groups of nude mice treated with cisplatin showed different degrees of weight loss. B Growth of the transplanted tumor in the UCA1 knockdown group was significantly inhibited by cisplatin. C Transplanted tumor in the A549/DDP-Lenti-shNC + DDP and A549/DDP-Lenti-shUCA1 + DDP groups. (D) Weight of the transplanted tumor was significantly lower in the A549/DDP-Lenti-shUCA1 + DDP group than in the A549/DDP-Lenti-shNC + DDP group. NS not significant. *P < 0.05, **P < 0.01, ***P < 0.001