From: Mechanistic study of lncRNA UCA1 promoting growth and cisplatin resistance in lung adenocarcinoma
Identified by | Protein ID | Function | Ref. |
---|---|---|---|
Both UCA1_sense and UCA1_antisense | sp|P04406|G3P_HUMAN | Inhibit cytarabine resistance of A549 cells | [26] |
sp|P07437|TBB5_HUMAN | Be linked to paclitaxel chemoresistance of ovarian cancer cells | [27] | |
sp|P25705|ATPA_HUMAN | Lead to 5-FU resistance of colon cancer cells | [28] | |
sp|P60174|TPIS_HUMAN | Be an anti-drug resistance agent in gastric cancer | [29] | |
sp|P00338|LDHA_HUMAN | serve an important role in docetaxel resistance in castration‑resistant prostate cancer | [30] | |
sp|P07737|PROF1_HUMAN | Synergize with chemotherapeutic drugs to induce tumor cell death | [31] | |
sp|P31943|HNRH1_HUMAN | Result in acquired chemoresistance to thymidine phosphorylase activated fluoropyrimidine anticancer drugs | [32] | |
sp|O43175|SERA_HUMAN | Be a critical driver for sorafenib resistance in hepatocellular carcinoma | [33] | |
sp|P15924|DESP_HUMAN | Increase the sensitivity to anticancer drug-induced apoptosis in NSCLC | [34] | |
sp|P04792|HSPB1_HUMAN | Inhibit cell apoptosis induced by paclitaxel in ovarian cancer | [35] | |
sp|P06733|ENOA_HUMAN | Be a partner protein of fibroblast growth factor receptor‐like 1 promoting chemoresistance of small‐cell lung cancer | [36] | |
UCA1_sense | sp|Q8N163|CCAR2_HUMAN | Promote drug resistance of colonospheres colon cancer cells | [37] |
sp|P11908|PRPS2_HUMAN | Be a target gene regulated by miRNAs which co-regulate vincristine resistance in childhood acute lymphoblastic leukemia | [38] | |
sp|Q13045|FLII_HUMAN | Silencing of FLI1 sensitizes the resistant cells to BRAF inhibitors in melanoma cells | [39] | |
sp|Q9Y6E2|BZW2_HUMAN | Promote rapamycin resistance of hepatocellular carcinoma cells | [40] | |
sp|P60981|DEST_HUMAN | Be a differentially expressed protein related to platinum resistance in ovarian cancer | [41] | |
sp|Q05639|EF1A2_HUMAN | Inhibit chemotherapy-induced apoptosis resulting in chemoresistance | [42] | |
sp|Q92769|HDAC2_HUMAN | BE a target to overcome therapeutic resistance of adenocarcinoma against chemotherapeutics in pancreatic cancer | [43] | |
sp|P51991|ROA3_HUMAN | Be upregulated in cisplatin-resistant breast cancer cells | [44] | |
sp|P33993|MCM7_HUMAN | Be inhibited by simvastatin to suppress tamoxifen-resistant breast cancer cells growth | [45] | |
sp|P14174|MIF_HUMAN | As a therapeutic target for overcoming resistance to proteasome inhibitors in myeloma | [46] | |
UCA1_antisense | sp|P80723|BASP1_HUMAN | Interact with oestrogen receptor α and modify the tamoxifen response in breast cancer | [47] |
sp|P14866|HNRPL_HUMAN | Knockdown of HNRPL enhanced the level of DNA breakage and sensitivity of colorectal cancer cells to oxaliplatin | [48] | |
sp|Q15019|SEPT2_HUMAN | LncRNA FGD5-AS1/miR-497-5p/SEPT2 axis increased cisplatin-resistance in laryngeal squamous cell carcinoma | [49] | |
sp|Q15717|ELAV1_HUMAN | Contribute to TRAIL resistance by restricting death receptor 4 expression in pancreatic cancer | [50] | |
sp|P13797|PLST_HUMAN | Be a critical regulator of paclitaxel sensitivity of MDA-MB-231 cells | [51] | |
sp|P21333|FLNA_HUMAN | Modulate chemosensitivity to docetaxel in triple-negative breast cancer through the MAPK/ERK pathway | [52] | |
sp|P06493|CDK1_HUMAN | Cooperate with UBE2C to promote cisplatin resistance in ovarian cancer | [53] | |
sp|P47929|LEG7_HUMAN | Be a potential predictive marker of chemotherapy resistance in oral squamous cell carcinoma | [54] | |
sp|Q8TEX9|IPO4_HUMAN | Enhance cervical cancer cisplatin sensitivity | [55] | |
sp|Q9P258|RCC2_HUMAN | Block spontaneous- or staurosporine-induced apoptosis in three cancer cell lines | [56] |