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Fig. 1 | Cancer Cell International

Fig. 1

From: ALDOA inhibits cell cycle arrest induced by DNA damage via the ATM-PLK1 pathway in pancreatic cancer cells

Fig. 1

ALDOA participated in the regulation of the DDR. A qRT-PCR analysis of the knockdown efficiency of shALDOA. B Western blotting was applied to analyse the knockdown efficiency of shALDOA. C KEGG analysis of the differentially expressed genes from the RNA sequencing conducted on PANC-1 and SW1990 cells showed the core enriched signalling pathways in ALDOA-silenced cells versus NC cells. D GSEA was applied to analyse the signalling pathway enrichment in siALDOA versus siNC PANC-1 and SW1990 cells. E Cell cycle analysis via flow cytometry revealed obvious arrest in the G2/M phase. F qRT-PCR analysis of the expression of genes related to DNA repair

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Cancer Cell International

ISSN: 1475-2867

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