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Table 1 Genotype frequencies of rs11016798, rs487120, rs557311 and rs1711654 and their associations with glioma risk

From: An insertion variant of MGMT disrupts a STAT1 binding site and confers susceptibility to glioma

Variants Genotypea Patients (n = 402)
No. (%)
Controls (n = 654)
No. (%)
ORb (95 %CI) P
rs11016798 CC 135 (34.61) 186 (29.02) 1.00 (reference)  
CT 201 (51.54) 318 (49.61) 0.90 (0.68–1.21) 0.491
TT 54 (13.85) 137 (21.37) 0.57 (0.39–0.85) 0.006
TT vs. CC + CT    0.61 (0.43–0.86) 0.005
rs487120 TT 152 (38.00) 265 (40.65) 1.00 (reference)  
CT 190 (47.50) 294 (45.09) 1.13 (0.86–1.49) 0.385
CC 58 (14.50) 93 (14.26) 1.05 (0.71–1.56) 0.808
rs557311 GG 167 (41.75) 309 (47.61) 1.00 (reference)  
AG 185 (46.25) 266 (40.99) 1.28 (0.98–1.68) 0.072
AA 48 (12.00) 74 (11.40) 1.13 (0.74–1.73) 0.580
rs1711654 TT 190 (47.62) 325 (50.31) 1.00 (reference)  
CT 169 (42.36) 251 (38.85) 1.17 (0.89–1.53) 0.268
CC 40 (10.02) 70 (10.84) 1.01 (0.65–1.57) 0.963
  1. OR odds ratios, CI confidence interval
  2. aSome samples failed to genotype
  3. bData were calculated by logistic regression, adjusted for age and sex