Fig. 7
From: Midkine promotes glioblastoma progression via PI3K-Akt signaling
MDK acts via PI3K-Akt signaling to influence GBM cell proliferation, migration, and invasion. Western blot analysis of p-Akt, Akt, p-ERK, ERK, p-PI3K, PI3K and β-actin in GBM cell lines T98G and U87-MG in which MDK was knocked down (KD), and in GBM cell lines A172 and U251-MG in which MDK was overexpressed (OE). Negative control (NC) cells were also analyzed in parallel. MDK: midkine; GBM: glioblastoma; IB: immunoblotting