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Fig. 1 | Cancer Cell International

Fig. 1

From: Transcriptional alterations of protein coding and noncoding RNAs in triple negative breast cancer in response to DNA methyltransferases inhibition

Fig. 1

Gene expression analysis of MDA-MB-231 and BT-549 TNBC cells treated with DNMT inhibitors. a Hierarchical clustering of MDA-MB-231 and BT-549 TNBC cells treated with Decitabine, 5-Azacytidine, or DMSO control based on differentially expressed genes between the two groups. Each column represents one sample and each row represents a gene. Expression level of each gene (log2) in a single sample is depicted according to the color scale. Enriched functional categories based on gene Ontology (GO) analysis are displayed on the left side. b Principal component analysis (PCA) for the RNA transcriptome of MDA-MB-231 and BT-549 TNBC cells treated with Decitabine, 5-Azacytidine, or DMSO control

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Cancer Cell International

ISSN: 1475-2867

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