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Table 1 Distribution of clinical variables among total, high and low GGT/ALT groups

From: Serum GGT/ALT ratio predicts vascular invasion in HBV-related HCC

Variables

Total (n = 558)

Low (n = 365)

High (n = 193)

P

Age, n (%)

   

1

 ≤ 60

422 (75.63)

291 (75.58)

131 (75.72)

 

 > 60

136 (24.37)

94 (24.42)

42 (24.28)

 

Sex, n (%)

   

0.003

 Female

84 (15.05)

70 (18.18)

14 (8.09)

 

 Male

474 (84.95)

315 (81.82)

159 (91.91)

 

ALT, n(%)

   

 < 0.001

  ≤ 56

471 (84.41)

299 (77.66)

172 (99.42)

 

  > 56

87 (15.59)

86 (22.34)

1 (0.58)

 

Albumin, n (%)

   

0.057

  ≤ 40

268 (48.03)

211 (54.81)

79 (45.66)

 

  > 40

290 (51.97)

174 (45.19)

94 (54.34)

 

TB, n (%)

   

0.657

  ≤ 20

503 (90.14)

349 (90.65)

154 (89.02)

 

  > 20

55 (9.86)

36 (9.35)

19 (10.98)

 

AFP, n (%)

   

0.399

  ≤ 400

402 (72.04)

282 (73.25)

120 (69.36)

 

  > 400

156 (27.96)

103 (26.75)

53 (30.64)

 

Cirrhosis, n (%)

   

0.904

 No

116 (20.79)

79 (20.52)

37 (21.39)

 

 Yes

442 (79.21)

306 (79.48)

136 (78.61)

 

Size, n (%)

   

 < 0.001

  ≤ 5

360 (64.52)

272 (70.75)

88 (50.87)

 

  > 5

198 (35.48)

113 (29.35)

85 (49.13)

 

Number, n (%)

   

0.518

 Solitary

468 (83.87)

326 (84.68)

142 (82.08)

 

 Multiple

90 (16.13)

59 (15.32)

31 (17.92)

 

Vascular invasion, n (%)

   

 < 0.001

 No

389 (69.71)

286 (74.29)

103 (59.54)

 

 Yes

169 (30.29)

99 (25.71)

70 (40.46)

 

Tumor capsule, n (%)

   

0.962

 Absence

354 (63.44)

245 (63.64)

109 (63.01)

 

 Presence

204 (36.56)

140 (36.37)

64 (36.99)

 

Differential, n (%)

   

0.042

 Good

184 (32.97)

269 (69.87)

105 (60.69)

 

 Moderate/poor

374 (67.03)

116 (30.13)

68 (39.31)

 

BCLC, n (%)

   

 < 0.001

 A

344 (61.65)

260 (67.53)

84 (48.55)

 

 B

176 (31.54)

108 (28.05)

68 (39.30)

 

 C

38 (6.81)

17 (4.42)

21 (12.14)

 

GGT, n (%)

   

 < 0.001

  ≤ 50

272 (48.75)

261 (67.79)

11 (6.36)

 

  > 50

286 (51.25)

124 (32.21)

162 (93.64)

 

ALBI Grade, n (%)

   

0.007

 A

399 (71.51)

289 (75.06)

110 (63.58)

 

 B

159 (28.50)

96 (24.90)

63 (36.42)

 
  1. ALT, Alanine aminotransferase; TB, Total Bilirubin; AFP, α-fetoprotein; BCLC, Barcelona Clinic Liver Cancer staging; GGT, γ-Glutamyl Transpeptidase; ALBI grade, Albumin-Bilirubin Grade