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Table 1 Distribution of clinical variables among total, high and low GGT/ALT groups

From: Serum GGT/ALT ratio predicts vascular invasion in HBV-related HCC

Variables Total (n = 558) Low (n = 365) High (n = 193) P
Age, n (%)     1
 ≤ 60 422 (75.63) 291 (75.58) 131 (75.72)  
 > 60 136 (24.37) 94 (24.42) 42 (24.28)  
Sex, n (%)     0.003
 Female 84 (15.05) 70 (18.18) 14 (8.09)  
 Male 474 (84.95) 315 (81.82) 159 (91.91)  
ALT, n(%)      < 0.001
  ≤ 56 471 (84.41) 299 (77.66) 172 (99.42)  
  > 56 87 (15.59) 86 (22.34) 1 (0.58)  
Albumin, n (%)     0.057
  ≤ 40 268 (48.03) 211 (54.81) 79 (45.66)  
  > 40 290 (51.97) 174 (45.19) 94 (54.34)  
TB, n (%)     0.657
  ≤ 20 503 (90.14) 349 (90.65) 154 (89.02)  
  > 20 55 (9.86) 36 (9.35) 19 (10.98)  
AFP, n (%)     0.399
  ≤ 400 402 (72.04) 282 (73.25) 120 (69.36)  
  > 400 156 (27.96) 103 (26.75) 53 (30.64)  
Cirrhosis, n (%)     0.904
 No 116 (20.79) 79 (20.52) 37 (21.39)  
 Yes 442 (79.21) 306 (79.48) 136 (78.61)  
Size, n (%)      < 0.001
  ≤ 5 360 (64.52) 272 (70.75) 88 (50.87)  
  > 5 198 (35.48) 113 (29.35) 85 (49.13)  
Number, n (%)     0.518
 Solitary 468 (83.87) 326 (84.68) 142 (82.08)  
 Multiple 90 (16.13) 59 (15.32) 31 (17.92)  
Vascular invasion, n (%)      < 0.001
 No 389 (69.71) 286 (74.29) 103 (59.54)  
 Yes 169 (30.29) 99 (25.71) 70 (40.46)  
Tumor capsule, n (%)     0.962
 Absence 354 (63.44) 245 (63.64) 109 (63.01)  
 Presence 204 (36.56) 140 (36.37) 64 (36.99)  
Differential, n (%)     0.042
 Good 184 (32.97) 269 (69.87) 105 (60.69)  
 Moderate/poor 374 (67.03) 116 (30.13) 68 (39.31)  
BCLC, n (%)      < 0.001
 A 344 (61.65) 260 (67.53) 84 (48.55)  
 B 176 (31.54) 108 (28.05) 68 (39.30)  
 C 38 (6.81) 17 (4.42) 21 (12.14)  
GGT, n (%)      < 0.001
  ≤ 50 272 (48.75) 261 (67.79) 11 (6.36)  
  > 50 286 (51.25) 124 (32.21) 162 (93.64)  
ALBI Grade, n (%)     0.007
 A 399 (71.51) 289 (75.06) 110 (63.58)  
 B 159 (28.50) 96 (24.90) 63 (36.42)  
  1. ALT, Alanine aminotransferase; TB, Total Bilirubin; AFP, α-fetoprotein; BCLC, Barcelona Clinic Liver Cancer staging; GGT, γ-Glutamyl Transpeptidase; ALBI grade, Albumin-Bilirubin Grade