From: Serum GGT/ALT ratio predicts vascular invasion in HBV-related HCC
Risks | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | |
Age, n (%) | ||||
  ≤ 60 | Reference |  | Reference |  |
  > 60 | 0.46 (0.29, 0.74) |  < 0.001 | 0.44 (0.27, 0.74) | 0.001 |
Sex, n (%) | ||||
 Female | Reference |  |  |  |
 Male | 1.36 (0.8, 2.32) | 0.245 |  |  |
Albumin, n (%) | ||||
  ≤ 40 | Reference |  |  |  |
  > 40 | 1.26 (0.88, 1.81) | 0.208 |  |  |
TB, n (%) | ||||
  > 20 | Reference |  |  |  |
  ≤ 20 | 0.97 (0.53, 1.77) | 0.916 |  |  |
AFP, n (%) | ||||
  ≤ 400 | Reference |  | Reference |  |
  > 400 | 2.3 (1.56, 3.4) |  < 0.001 | 1.63 (1.06, 2.51) | 0.026 |
Cirrhosis, n (%) | ||||
 No | Reference |  |  |  |
 Yes | 1.24 (0.79, 1.97) | 0.344 |  |  |
Size, n (%) | ||||
  ≤ 5 | Reference |  |  |  |
  > 5 | 2.96 (2.04, 4.31) |  < 0.001 | 2.15 (1.42, 3.24) |  < 0.001 |
Number, n (%) | ||||
 Solitary | Reference |  | Reference |  |
 Multiple | 1.68 (1.05, 2.68) | 0.032 | 1.44 (0.85, 2.41) | 0.175 |
Tumor capsule, n (%) | ||||
 Absence | Reference |  | Reference |  |
 Presence | 1.79 (1.24, 2.59) | 0.002 | 1.64 (1.09, 2.47) | 0.018 |
Differential, n (%) | ||||
 Good | Reference |  | Reference |  |
 Moderate/poor | 3.44 (2.35, 5.04) |  < 0.001 | 2.90 (1.93, 4.36) |  < 0.001 |
BCLC, n (%) | ||||
 A | Reference |  |  |  |
 B | 2.95 (2.46, 3.43) |  < 0.001 | 2.62 (2.21, 3.03) |  < 0.001 |
 C | 3.02 (2.63, 3.72) |  < 0.001 | 2.76 (2.33, 3.15) |  < 0.001 |
ALBI Grade, n (%) | ||||
 A | Reference |  | Reference |  |
 B | 1.95 (1.23, 2.67) | 0.003 | 1.44 (0.93, 2.21) | 0.1 |
GGT/ALT | ||||
  ≤ 2.95 | Reference |  | Reference |  |
  > 2.95 | 1.96 (1.34, 2.87) |  < 0.001 | 1.60 (1.05, 2.43) | 0.030 |