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Table 2 Univariate and multivariate logistic analysis of prognostic factors associated with vascular invasion

From: Serum GGT/ALT ratio predicts vascular invasion in HBV-related HCC

Risks Univariate analysis Multivariate analysis
OR (95% CI) P OR (95% CI) P
Age, n (%)
  ≤ 60 Reference   Reference  
  > 60 0.46 (0.29, 0.74)  < 0.001 0.44 (0.27, 0.74) 0.001
Sex, n (%)
 Female Reference    
 Male 1.36 (0.8, 2.32) 0.245   
Albumin, n (%)
  ≤ 40 Reference    
  > 40 1.26 (0.88, 1.81) 0.208   
TB, n (%)
  > 20 Reference    
  ≤ 20 0.97 (0.53, 1.77) 0.916   
AFP, n (%)
  ≤ 400 Reference   Reference  
  > 400 2.3 (1.56, 3.4)  < 0.001 1.63 (1.06, 2.51) 0.026
Cirrhosis, n (%)
 No Reference    
 Yes 1.24 (0.79, 1.97) 0.344   
Size, n (%)
  ≤ 5 Reference    
  > 5 2.96 (2.04, 4.31)  < 0.001 2.15 (1.42, 3.24)  < 0.001
Number, n (%)
 Solitary Reference   Reference  
 Multiple 1.68 (1.05, 2.68) 0.032 1.44 (0.85, 2.41) 0.175
Tumor capsule, n (%)
 Absence Reference   Reference  
 Presence 1.79 (1.24, 2.59) 0.002 1.64 (1.09, 2.47) 0.018
Differential, n (%)
 Good Reference   Reference  
 Moderate/poor 3.44 (2.35, 5.04)  < 0.001 2.90 (1.93, 4.36)  < 0.001
BCLC, n (%)
 A Reference    
 B 2.95 (2.46, 3.43)  < 0.001 2.62 (2.21, 3.03)  < 0.001
 C 3.02 (2.63, 3.72)  < 0.001 2.76 (2.33, 3.15)  < 0.001
ALBI Grade, n (%)
 A Reference   Reference  
 B 1.95 (1.23, 2.67) 0.003 1.44 (0.93, 2.21) 0.1
GGT/ALT
  ≤ 2.95 Reference   Reference  
  > 2.95 1.96 (1.34, 2.87)  < 0.001 1.60 (1.05, 2.43) 0.030
  1. TB, Total Bilirubin; AFP, α-fetoprotein; BCLC, Barcelona Clinic Liver Cancer staging; ALBI grade, Albumin-Bilirubin Grade; GGT, γ-Glutamyl Transpeptidase; ALT, Alanine aminotransferase