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Table 2 C-index for the prediction of PFS in the study cohorts

From: Dynamic serum biomarkers to predict the efficacy of PD-1 in patients with nasopharyngeal carcinoma

Factors Training cohort Validation cohort Total cohort
C-index (95% CI) P-value C-index (95% CI) P-value C-index (95% CI) P-value
TMN stage 0.53 (0.465–0.606)   0.513 (0.410–0.615)   0.518 (0.460–0.577)  
Nomogram 0.662 (0.577–0.746)   0.630 (0.509–0.752)   0.650 (0.581–0.718)  
Nomogram vs TNM stage   0.002   0.105    < 0.001
  1. C-index concordance index, CI confidence interval, TNM tumor/node/metastasis
  2. Nomogram: Risk scores + M stage
  3. P-values are calculated based on normal approximation using rcorrp.cens package function in Hmisc in R