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Fig. 5 | Cancer Cell International

Fig. 5

From: Exosomal lncRNA SNHG10 derived from colorectal cancer cells suppresses natural killer cell cytotoxicity by upregulating INHBC

Fig. 5

LncRNA SNHG10-mediated regulation of INHBC. A Heatmap diagram of DEGs in NK92-MI cells between two groups: one group was incubated with exosomes derived from SW480 cells transfected with vector (Vector exo), whereas the other group was incubated with exosomes derived from SW480 cells that overexpressed lncRNA SNHG10 (oe-lnc-SNHG10 exo). Red, upregulated; green, downregulated. B Top 15 upregulated KEGG enrichment pathways. The KEGG pathways are indicated on the left, the P values are indicated on the right. C qRT-PCR validation of four selected DEGs between the Vector exo group and oe-lnc-SNHG10 exo group. D Protein level of INHBC in NK92-MI cells in the Vector exo group or oe-lnc-SNHG10 exo group. GAPDH was used to normalize gene expression. t-test, *P < 0.05, **P < 0.01

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Cancer Cell International

ISSN: 1475-2867

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