Fig. 2
From: EZR promotes pancreatic cancer proliferation and metastasis by activating FAK/AKT signaling pathway
Significantly upregulated EZR expression in PC tissues and PC cell lines, PC patients with high expression of EZR had a poor diagnosis. A GEPIA data of EZR expression in PC tissues and normal pancreatic tissues (*p < 0.05). B 26 paired cancer tissues and paracancer tissues were collected from patients, EZR was aberrantly upregulated in PC tissues compared with paracancer tissues (**p < 0.01). C, D RT-qPCR and WB assessed EZR expression in normal pancreatic cell line (HPDE) and PC cell lines (AsPC-1, PANC-1, BXPC-3, and MIA PaCa-2). E Immunohistochemical detection of EZR expression in PC tissues compared with paracancer tissues. F The difference of histochemistry score between PC tissues and paracancer tissues. G, H Kaplan–Meier survival analysis verified high expression of EZR had a poor diagnosis in 26 PC samples. *p < 0.05, **p < 0.01, ***p < 0.001