Licorice extract inhibits growth of non-small cell lung cancer by down-regulating CDK4-Cyclin D1 complex and increasing CD8+ T cell infiltration

Table 1 Chemical information and pharmacokinetics parameters of the 23 active compounds of licorice

MOL-ID	Compounds	Categories	OB	DL	Degree
MOL005008	Glycyrrhiza flavonol A	Flavonoids	41.28	0.60	30
MOL001484	Inermine	Flavonoids	75.18	0.54	35
MOL000211	Mairin	Saponins	55.38	0.78	16
MOL002311	Glycyrol	Coumestans	90.78	0.67	14
MOL004808	Glyasperin B	Others	65.22	0.44	31
MOL004810	Glyasperin F	Others	75.84	0.54	33
MOL004820	Kanzonols W	Flavonoids	50.48	0.52	38
MOL004855	Licoricone	Flavonoids	63.58	0.47	23
MOL004863	3-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-(3-methylbut-2-enyl)chromon	Others	66.37	0.41	26
MOL004879	Glycyrin	Coumarins	52.61	0.47	22
MOL004885	Licoisoflavanone	Flavonoids	52.47	0.54	31
MOL004891	Shinpterocarpin	Flavonoids	80.3	0.73	44
MOL004903	Liquiritin	Flavonoids	65.69	0.74	21
MOL004904	Licopyranocoumarin	Flavonoids	80.36	0.65	25
MOL004908	Glabridin	Flavonoids	53.25	0.47	39
MOL004912	Glabrone	Flavonoids	52.51	0.5	38
MOL004914	1,3-Dihydroxy-8,9-dimethoxy-6-benzofurano[3,2-c]chromenone	Others	62.9	0.53	20
MOL004959	1-Methoxyphaseollidin	Flavonoids	69.98	0.64	35
MOL005001	Gancaonin H	Others	50.1	0.78	30
MOL005003	Licoagrocarpin	Flavonoids	58.81	0.58	37
MOL005007	Glyasperins M	Flavonoids	72.67	0.59	39
MOL005012	Licoagroisoflavone	Flavonoids	57.28	0.49	36
MOL005017	Phaseol	Coumestans	78.77	0.58	21

ISSN: 1475-2867