Incidence of suicide among adolescent and young adult cancer patients: a population-based study

Table 1 Incidence of suicide among AYA cancer patients by demographic and tumor characteristics

Characteristic	Patients with cancer		Suicide		Suicide per 100,000 Person-years ^a	SMR ^ab	95% CI
Characteristic	No	%	No	%	Suicide per 100,000 Person-years ^a	SMR ^ab	95% CI
Sex
Male	223,123	38.97%	658	67.07%	33.75	1.484	1.374–1.601
Female	349,377	61.03%	323	32.93%	9.01	1.449	1.299–1.616
Race
White	455,982	79.65%	901	91.85%	19.55	1.27	1.189–1.355
Black	58,305	10.18%	34	3.47%	7.46	0.78	0.558–1.092
Other	58,213	10.17%	46	4.69%	9.83	1.039	0.778–1.387
Material status
Married	259,679	45.36%	376	38.33%	13.13	0.908	0.821–1.005
Unmarried	263,589	46.04%	519	52.91%	24.09	1.644	1.508–1.792
Unkmon	49,232	8.60%	86	8.77%	18.72	1.312	1.062–1.621
Stage at presentation
In situ	43,246	7.55%	66	6.73%	13.48	0.927	0.728–1.180
Localized	214,419	37.45%	386	39.35%	14.76	1.019	0.922–1.126
Regional	99,829	17.44%	142	14.48%	15.23	1.06	0.899–1.249
Distant	65,836	11.50%	66	6.73%	20.87	1.444	1.134–1.838
Unstaged/Unknown	149,170	26.06%	321	32.72%	29.28	1.94	1.739–2.164
No of primary
Single	475,758	83.10%	852	86.85%	19.07	1.332	1.246–1.425
Multiple	96,742	16.90%	129	13.15%	11.67	0.828	0.697–0.984
Year of diagnosis
1973–1983	50,407	8.80%	182	18.55%	16.64	1.176	1.017–1.360
1984–1994	89,064	15.56%	322	32.82%	22.28	1.552	1.391–1.731
1995–2005	184,245	32.18%	314	32.01%	15.63	1.085	0.971–1.211
2006–2015	248,784	43.46%	163	16.62%	16.27	1.136	0.975–1.325
All AYA patients with cancer	572,500	1	981	1	17.68	1.234	1.159–1.313

SEER Surveillance, epidemiology, and end results, SMR standardized mortality ratio
^aAdjusted to the age distribution in the population served by the SEER program.
^bFor the categories of sex and race, SMR reference population was the specific category in the general US subpopulation (eg, the SMR for male AYAs is the observed number of suicides in male AYA patients divided by the expected number of suicides based on the rate in men in the general AYA population). For marital status, stage at presentation, number of primary tumors, and year of diagnosis, SMR reference population is the entire general US AYA population from 1969 through 2015.

ISSN: 1475-2867