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Fig. 3 | Cancer Cell International

Fig. 3

From: Risk factors affect accurate prognosis in ASXL1-mutated acute myeloid leukemia

Fig. 3

Transplantation can improve OS (A) and EFS (B) of ASXL1+ AML patients. The factors that had adverse impact on OS and EFS are defined as high risk factors, including age ≥ 60 years, WBC count ≥ 50 × 109/L, FLT3-ITD mutations, RUNX1 mutations, and absence of AML1-ETO fusion gene. ASXL1 mutations without any risk factor were classified as single-hit ASXL1+ AML. ASXL1 mutations together with any of the risk factors was referred to as double-hit ASXL1+ AML. ASXL1 mutations along with any two or more of the risk factors were designated as triple-hit ASXL1+ AML

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