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Fig. 5 | Cancer Cell International

Fig. 5

From: Role of RhoC in cancer cell migration

Fig. 5

RhoC regulates cell contraction. RhoC is regulated by RhoGEF TEM4tem4 [106] and RhoD/PAK6 [147] in the process of cell contraction, in which RhoC plays a dual role, by first regulating the redistribution of myosin II through ROCK [148], and then managing the activity of MLCP through ROCK and MRK [149, 150], to modulate myosin and regulate cell contraction

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