Fig. 5From: Role of RhoC in cancer cell migrationRhoC regulates cell contraction. RhoC is regulated by RhoGEF TEM4tem4 [106] and RhoD/PAK6 [147] in the process of cell contraction, in which RhoC plays a dual role, by first regulating the redistribution of myosin II through ROCK [148], and then managing the activity of MLCP through ROCK and MRK [149, 150], to modulate myosin and regulate cell contractionBack to article page