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Fig. 2 | Cancer Cell International

Fig. 2

From: FAM49B promotes breast cancer proliferation, metastasis, and chemoresistance by stabilizing ELAVL1 protein and regulating downstream Rab10/TLR4 pathway

Fig. 2

High expression of FAM49B in human BC. A Expression status of FAM49B in matched normal (N) and cancerous (T) regions isolated from BC patients following western blotting. Expression levels of FAM49B, ER, and HER2, as per immunohistochemical staining (B–D). Blue arrow represents staining in the nucleus; black arrow represents staining in the cytoplasm; red arrow represents staining in the cytomembrane. E Kaplan–Meier survival curves showing survival in 180 BC patients, with respect to FAM49B expression. Results are presented as the mean ± SD. The statistical significance was assessed by Student’s t-test; **p < 0.01

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