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Fig. 1 | Cancer Cell International

Fig. 1

From: Upregulation of SNTB1 correlates with poor prognosis and promotes cell growth by negative regulating PKN2 in colorectal cancer

Fig. 1

Gene expression profiling and high content screening suggest carcinogenic potential of SNTB1 in CRC. a Differentially expressed genes (DEGs) were analyzed from our previous microarray analysis between 14 pairs of colorectal cancer (CRC) tissues (T) and adjacent normal tissues (N). Heatmap of the 8 selected DEGs mRNA expression levels are presented. Blue color indicates low expression and red color high expression. b HCT116 cells were transduced with lentivirus encoding shRNAs against these 8 DEGs (SNTB1, PLEKHG4, JPH1, CTPS1, LRRC6, LY6G6F, PLCB4 and LRP8), and cell growth was measured using the using the Pathway 855 high-content image analysis platform. The representative images were taken at a magnification of 200×. c Heatmap showing the growth of HCT116 cells. Data were normalized to cell number on day 1 and represented as fold change

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Cancer Cell International

ISSN: 1475-2867

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