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Fig. 2 | Cancer Cell International

Fig. 2

From: Upregulation of SNTB1 correlates with poor prognosis and promotes cell growth by negative regulating PKN2 in colorectal cancer

Fig. 2

Levels of SNTB1 mRNA and protein in colorectal cancer tissues. a SNTB1 mRNA expression in CRC tissues (T: n=79) and non-cancerous colorectal tissues (N: n=15) on the CRC cDNA chip was analyzed by qPCR. GAPDH was used as an internal control. *P < 0.05. b, c SNTB1 mRNA expression in CRC tissues (T) and non-cancerous colorectal tissues (N) from GEO (b) and TCGA (c) were analyzed. d, e SNTB1 protein expression in CRC tissues (T) and non-cancerous colorectal tissues (N) was determined by immunohistochemistry of a tissue microarray. Representative images were taken at magnification of 40× or 200× (right panel); the IHC score was calculated as intensity score × percentage score (left panel, see Methods). *P < 0.05. f, g Kaplan-Meier plots of survival of CRC patients, stratified by SNTB1 mRNA expression based on cDNA array (f) and TCGA database (g). Survival was analyzed with log-rank test

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Cancer Cell International

ISSN: 1475-2867

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