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Fig. 4 | Cancer Cell International

Fig. 4

From: Upregulation of SNTB1 correlates with poor prognosis and promotes cell growth by negative regulating PKN2 in colorectal cancer

Fig. 4

SNTB1 knockdown induces cell cycle arrest and cell apoptosis in colorectal cancer (CRC) cells. HCT116 and RKO cells were transduced with lentivirus encoding either anti-SNTB1 small hairpin RNA (sh-SNTB1) or control shRNA (sh-Ctrl). a Cell cycle progression in HCT116 (upper panel) and RKO (lower panel) cells was determined by PI staining and FACS analysis. Representative plots (left panel) and percentage of cells (right panel) at different stages (G0/G1, G2/M and S phases) are presented. *P < 0.05. b Apoptosis of HCT116 (upper panel) and RKO (lower panel) cells was determined by Annexin V staining and FACS analysis. Representative plots (left panel) and percentage of apoptotic cells (right panel) are presented. *P < 0.05. All experiments were performed in triplicate

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Cancer Cell International

ISSN: 1475-2867

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