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Fig. 1 | Cancer Cell International

Fig. 1

From: Hypomethylation and downregulation of miR-23b-3p are associated with upregulated PLAU: a diagnostic and prognostic biomarker in head and neck squamous cell carcinoma

Fig. 1

PLAU filtering and its expression in HNSCC. a Fifteen three-crossing and 115 two-crossing DEGs were filtered among three public datasets. b KM survival analysis showed that high expression of PLAU was associated with worse prognosis of patients with HNSCC. The mRNA level of PLAU was significantly higher in HNSCC compared to the normal para-carcinoma tissues from TCGA database (c) and our patients (d). The mRNA level of PLAU was especially higher in the p53 mutant group compared to the nonmutant group (e). The protein level of PLAU was much higher in HNSCC (left) than in the normal tissues of the oral mucosa (right) both from THPA (f) and our patients (g)

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Cancer Cell International

ISSN: 1475-2867

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