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Table 1 Association between PLAU expression and clinical variables in patients with HNSCC

From: Hypomethylation and downregulation of miR-23b-3p are associated with upregulated PLAU: a diagnostic and prognostic biomarker in head and neck squamous cell carcinoma

Clinical variable Number PLAU expression p-value
Sex
 Male 368 7.96 ± 1.290 0.572
 Female 134 8.05 ± 1.301
Age (years)
 ≥ 60 256 7.97 ± 1.280 0.748
 < 60 221 7.98 ± 1.334
Tumor stage
 T1 34 7.58 ± 1.342 0.088
 T2 144 7.93 ± 1.296
 T3 133 7.93 ± 1.232
 T4 177 8.10 ± 1.277
Lymph metastasis
 N0 241 7.94 ± 1.291 0.552
 N1 81 8.10 ± 1.276
 N2 136 7.99 ± 1.261
Clinical stage
 I 25 7.90 ± 1.166 0.726
 II 81 7.93 ± 1.199
 III 90 7.99 ± 1.261
 IV 306 8.00 ± 1.339
Smoking status
 Yes 381 8.00 ± 1.252 0.529
 No 111 7.93 ± 1.380
  1. Complete data were unavailable in the TCGA database
  2. aTumor stage: T category of the TNM classification which described the primary tumor site and size
  3. bClinical stage: the TNM combinations were grouped into four less-detailed stages, including Stages I to Stage IV