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Fig. 8 | Cancer Cell International

Fig. 8

From: Integrated single-cell and bulk RNA sequencing analysis identifies a cancer associated fibroblast-related signature for predicting prognosis and therapeutic responses in colorectal cancer

Fig. 8

a–c The IC50 values of six anti-cancer drugs were predicted by pRRophetic algorithm and were Z-score normalized. The difference between high- and low-CAF risk groups of each drug in a TCGA COAD/READ, b GSE39582 and c GSE17536 cohort was compared by Wilcoxon test (** P < 0.01, *** P < 0.001). d–f TIDE analysis for predicting the likelihood of clinical response to immune checkpoint inhibitors in d TCGA COAD/READ, e GSE39582 and f GSE17536 cohort. Patients with a lower CAF risk score are more likely to respond from immune therapy

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Cancer Cell International

ISSN: 1475-2867

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