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Fig. 1 | Cancer Cell International

Fig. 1

From: The long non-coding RNA HOXA11-AS activates ITGB3 expression to promote the migration and invasion of gastric cancer by sponging miR-124-3p

Fig. 1

The lncRNA HOXA11-AS is up-regulated and correlated with miR-124-3p and ITGB3 RNA levels in gastric cancer tissues of patients. Expression of HOXA11-AS in GC tissues and paired adjacent normal tissues, respectively in cohort of this study (a), Lnc2Cancer 3.0 database (b) and GEPIA database (c). K–M Plotter Kaplan–Meier survival analysis of overall survival in GC patients based on HOXA11-AS expression (d) (P = 0.015). K–M Plotter Kaplan–Meier survival analysis of first progress survival in GC patients based on HOXA11-AS expression (e) (P = 0.084). ROC curve of HOXA11-AS diagnostic performance in gastric cancer patients (f). Association between the expressions of HOXA11-AS with that of miR-124-3p (g) and ITGB3 (h) in GC tissues. Relative luciferase activity of different transfection group in dual luciferase reporter assay (i). * P < 0.01

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