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Table 2 Predictive factors of OS

From: Carboxypeptidase N1 is anticipated to be a synergy metrics for chemotherapy effectiveness and prognostic significance in invasive breast cancer

Overall survival

Univariate analysis

Multivariate analysis

Cut off

HR

95% CI

P value

HR

95% CI

P value

Age (years)

60

1.053

0.552–2.008

0.875

   

Tumor size (cm)

5

2.018

1.003–4.06

0.049*

0.751

0.205–2.753

0.666

T stage

3

1.696

1.081–2.662

0.022*

1.421

0.707–2.856

0.323

N stage

3

1.507

1.115–2.038

0.008*

2.18

0.875–5.433

0.094

Pathologic stage

3

1.02

0.751–1.384

0.612

   

pT stage

3

2.3

1.332–3.971

0.003*

0.518

0.264–1.015

0.055

ER score

4

1.33

0.685–2.58

0.4

   

PR score

4

0.4

0.156–1.023

0.047*

0.38

0.102–1.418

0.15

HER2 score

4

1.983

0.454–1.611

0.036*

0.508

0.254–1.154

0.51

KI67 score

4

0.825

0.293–2.323

0.716

   

P53 score

4

1.024

0.541–1.939

0.475

   

CPN1 score

4

3.438

1.784–6.624

 < 0.001*

2.384

1.073–5.295

0.033*

  1. HR: Cox proportional hazard ratio, 95% CI: 95% confidence interval
  2. *Statistically significant (P < 0.05)
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Cancer Cell International

ISSN: 1475-2867

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