Fig. 9
From: Ferroptosis-related gene AKR1C1 predicts the prognosis of non-small cell lung cancer
AKR1C1 silencing inhibits the malignant phenotypes of NSCLC cells. A–C RT-qPCR and western blot results showed that AKR1C1 was successfully knocked out by siRNA in A549 cells and H1975 cells. *represents si-AKR1C1 vs. si-NC, *P < 0.05, **P < 0.01. D, E The effect of AKR1C1 silencing on cell proliferation were measured by CCK8 assay and colony formation assay. *represents si-AKR1C1 vs. si-NC, *P < 0.05, **P < 0.01. F Measurement of wound healing ability. Cells under different treatments were examined for migration to the wound area and photographed