Table 3 Cox model analysis of overall survival
Parameters | Relative risk (95% CI) | P-value |
|---|---|---|
Univariate | ||
 Age | 1.318(1.005–1.729) | 0.046 |
 Gender | 0.740(0.557–0.983) | 0.042 |
 Smoking | 1.009(0.767–1.327) | 0.949 |
 Alcohol | 0.877(0.644–1.194) | 0.405 |
 Histological grade | 0.828(0.643–1.067) | 0.144 |
 Stage | 1.767(1.212–2.577) | 0.003 |
 T classification | 1.386(1.114–1.723) | 0.003 |
 Lymph node metastasis | 1.346(1.117–1.622) | 0.002 |
 Distant metastasis | 1.050(0.818–1.348) | 0.701 |
 MKRN3 expression | 1.004(1.002–1.006) | 0.000 |
Multivariate | ||
 Lymph node metastasis | 1.721(1.358–2.158) | 0.000 |
 T classification | 1.916(1.389–2.643) | 0.000 |
 MKRN3 expression | 1.004(1.002–1.006) | 0.001 |