FABP4 is an independent risk factor for lymph node metastasis and poor prognosis in patients with cervical cancer

Table 3 Analysis of the risk factors for LNM in patients with CCa (N = 178)

Variables	Univariate regression analyses			Multivariate regression analyses
Variables	OR	95% CI	P	OR	95% CI	P
FABP4	1.62	1.215–2.160	0.001	1.582	1.110–2.254	0.011
M stage			< 0.001			0.028
M1 vs. M0	17.25	3.549–83.850	< 0.001	5.365	0.595–48.401	0.134
Unknown vs. M0	2.39	1.229–4.645	0.01	2.858	1.257–6.498	0.012
FIGO stage			< 0.001			< 0.001
Stage II vs. Stage I	1.033	0.397–2.687	0.947	0.881	0.318–2.442	0.808
Stage III vs. Stage I	24.792	5.266–116.725	< 0.001	32.671	6.435–165.881	< 0.001
Stage IV vs. Stage I	31.875	6.905–147.132	< 0.001	13.789	2.231–85.230	0.005
Unknown vs. Stage I	–	–	0.999	–		–
T stage			0.004			0.803
T2 vs. T1	1.725	0.798–3.728	0.165	–	–	0.441
T3 vs. T1	13.226	1.485–117.755	0.021	–	–	0.489
T4 vs. T1	4.761	1.480–15.321	0.009	–	–	0.345
Unknown vs. T1	6.613	1.219–35.878	0.029	–	–	0.761
Age	1.013	0.989–1.038	0.297	–	–	–
Histological Type SCC vs. AC	0.566	0.246–1.300	0.18	–	–	–

CCa cervical cancer, FIGO International Federation of Gynecology and Obstetrics, SCC squamous cell carcinoma, AC Adenocarcinoma

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