Table 2 Association between METTL5 and clinicopathological parameters in gastric cancer
Variables | Case (–) n% | Case ( +) n% | Case (+ +) n% | Case (+ + +) n% | PR% | r/ CI95% | p |
|---|---|---|---|---|---|---|---|
Gender | − 0.11/[− 0.29, 0.08], | 0.22 | |||||
Male | 32 | 27 | 16 | 0 | 57.33 | ||
Female | 11 | 17 | 10 | 0 | 71.05 | ||
Age | − 0.09/[− 0.27, 0.08] | 0.36 | |||||
≥ 60 | 20 | 25 | 14 | 0 | 66.10 | ||
< 60 | 23 | 19 | 12 | 0 | 57.41 | ||
Invasive extent | 0.26/[0.07, 0.41] | 0.01 | |||||
T1–2 | 7 | 18 | 11 | 0 | 80.56 | ||
T3–4 | 36 | 26 | 15 | 0 | 53.25 | ||
Lymph node metastasis | 0.18/[− 0.01, 0.37] | 0.05 | |||||
Yes | 31 | 22 | 15 | 0 | 54.41 | ||
No | 12 | 22 | 11 | 0 | 73.33 | ||
TNM stage | 0.08/[0.02, 0.22] | 0.03 | |||||
I | 4 | 18 | 9 | 0 | 87.10 | ||
II | 13 | 5 | 5 | 0 | 43.48 | ||
III | 21 | 18 | 11 | 0 | 58.00 | ||
IV | 5 | 3 | 1 | 0 | 44.44 | ||
Tumor location | 0.02/[0.00, 0.13] | 0.64 | |||||
Gastric body | 8 | 8 | 7 | 0 | 65.22 | ||
Gastric angle | 12 | 6 | 8 | 0 | 53.85 | ||
Antrum of stomach | 16 | 25 | 9 | 0 | 68.00 | ||
Preventriculus | 3 | 5 | 1 | 0 | 66.67 | ||
All | 4 | 0 | 1 | 0 | 20.00 | ||
Maximum diameter (cm) | − 0.03/[− 0.21, 0.13] | 0.76 | |||||
≤ 4 | 15 | 19 | 8 | 0 | 64.29 | ||
> 4 | 28 | 25 | 18 | 0 | 60.56 | ||
Differentiation degree | 0.23/[0.12, 0.41] | < 0.01 | |||||
Well/moderate | 1 | 9 | 12 | 0 | 95.45 | ||
Mucinous | 8 | 5 | 5 | 0 | 55.56 | ||
Poor | 29 | 23 | 8 | 0 | 51.67 | ||
Others | 5 | 7 | 1 | 0 | 61.54 | ||
Growth pattern | − 0.31/[− 0.50, − 0.12], | < 0.01 | |||||
Infiltrative | 39 | 36 | 16 | 0 | 57.14 | ||
Nested/cloddy | 4 | 8 | 10 | 0 | 81.82 | ||
Lymphatic/venous invasion | − 0.11/[− 0.28, 0.08] | 0.27 | |||||
Yes | 26 | 23 | 13 | 0 | 58.06 | ||
No | 17 | 21 | 13 | 0 | 66.67 | ||
Perineural invasion | − 0.30/[− 0.45, − 0.11], | < 0.01 | |||||
Yes | 37 | 33 | 14 | 0 | 55.95 | ||
No | 6 | 11 | 12 | 0 | 79.31 |