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Table 2 Association between METTL5 and clinicopathological parameters in gastric cancer

From: Expression and prognostic potential of ribosome 18S RNA m6A methyltransferase METTL5 in gastric cancer

Variables Case (–)
n%
Case ( +)
n%
Case (+ +)
n%
Case (+ + +)
n%
PR% r/ CI95% p
Gender       − 0.11/[− 0.29, 0.08], 0.22
 Male 32 27 16 0 57.33   
 Female 11 17 10 0 71.05   
Age       − 0.09/[− 0.27, 0.08] 0.36
 ≥ 60 20 25 14 0 66.10   
 < 60 23 19 12 0 57.41   
Invasive extent       0.26/[0.07, 0.41] 0.01
 T1–2 7 18 11 0 80.56   
 T3–4 36 26 15 0 53.25   
Lymph node metastasis       0.18/[− 0.01, 0.37] 0.05
 Yes 31 22 15 0 54.41   
 No 12 22 11 0 73.33   
TNM stage       0.08/[0.02, 0.22] 0.03
 I 4 18 9 0 87.10   
 II 13 5 5 0 43.48   
 III 21 18 11 0 58.00   
 IV 5 3 1 0 44.44   
Tumor location       0.02/[0.00, 0.13] 0.64
 Gastric body 8 8 7 0 65.22   
 Gastric angle 12 6 8 0 53.85   
 Antrum of stomach 16 25 9 0 68.00   
 Preventriculus 3 5 1 0 66.67   
 All 4 0 1 0 20.00   
Maximum diameter (cm)       − 0.03/[− 0.21, 0.13] 0.76
 ≤ 4 15 19 8 0 64.29   
 > 4 28 25 18 0 60.56   
Differentiation degree       0.23/[0.12, 0.41]  < 0.01
 Well/moderate 1 9 12 0 95.45   
 Mucinous 8 5 5 0 55.56   
 Poor 29 23 8 0 51.67   
 Others 5 7 1 0 61.54   
Growth pattern        − 0.31/[− 0.50, − 0.12],  < 0.01
 Infiltrative 39 36 16 0 57.14   
 Nested/cloddy 4 8 10 0 81.82   
Lymphatic/venous invasion        − 0.11/[− 0.28, 0.08] 0.27
 Yes 26 23 13 0 58.06   
 No 17 21 13 0 66.67   
Perineural invasion        − 0.30/[− 0.45, − 0.11],  < 0.01
 Yes 37 33 14 0 55.95   
 No 6 11 12 0 79.31   
  1. PR: positive rate. Negative ( −), light positive ( +), positive (+ +), strong positive (+ + +) staining
  2. The association of METTL5 expression with multitaxonomic variables, including TNM stage, Tumor location and differentiation degree, was analyzed by Kruskal–Wallis H- test of nonparametric test. For other dichotomous variables, Mann–Whitney U- test of nonparametric test was used