Table 3 Multivariate Cox analysis of gastric cancer
Risk factors | p-value | HR | 95% CI | |
|---|---|---|---|---|
The lower limit | The higher limit | |||
Gender | 0.33 | |||
Male | Reference | |||
Female | 0.67 | 0.30 | 1.50 | |
Age | 0.52 | |||
≥ 60 | Reference | |||
< 60 | 0.79 | 0.38 | 1.63 | |
METTL5 | < 0.05 | |||
High | Reference | |||
Low | 2.28 | 1.01 | 5.15 | |
Invasive extent | 0.71 | |||
T1–2 | Reference | |||
T3–4 | 0.58 | 0.03 | 10.18 | |
Lymph node metastasis | 0.72 | |||
Yes | Reference | |||
No | 0.66 | 0.07 | 6.11 | |
TNM stage | < 0.01 | |||
I | Reference | |||
II | 0.55 | 0.40 | 0.02 | 8.16 |
III | 0.31 | 10.20 | 0.12 | |
IV | 0.11 | 39.54 | 0.45 | 346.25 |
Tumor location | 0.02 | |||
Gastric body | Reference | |||
Gastric angle | < 0.01 | 0.18 | 0.06 | 0.55 |
Antrum of stomach | < 0.01 | 0.28 | 0.11 | 0.71 |
Preventriculus | 0.27 | 0.48 | 0.13 | 1.75 |
All | 0.12 | 0.33 | 0.07 | 1.37 |
Maximum diameter (cm) | 0.12 | |||
≤ 4 | Reference | |||
> 4 | 0.54 | 0.25 | 1.17 | |
Differentiation degree | 0.01 | |||
Well/moderate | Reference | |||
Mucinous | < 0.05 | 0.26 | 0.07 | 1.00 |
Poor | < 0.01 | 0.12 | 0.03 | 0.47 |
Others | 0.40 | 0.56 | 0.15 | 2.17 |
Growth pattern | 0.69 | |||
Infiltrative | Reference | |||
Nested/cloddy | 1.34 | 0.32 | 5.54 | |
Lymphatic/venous invasion | 0.72 | |||
Yes | Reference | |||
No | 0.66 | 0.07 | 6.11 | |
Perineural invasion | 0.02 | |||
Yes | Reference | |||
No | 0.14 | 0.03 | 0.70 | |