Fig. 8
From: RHBDF2 gene functions are correlated to facilitated renal clear cell carcinoma progression
RHBDF2 knockdown restricted renal clear cell tumor proliferation and migration. a Cell proliferation detection by Edu incorporation assay in 786-O cells and 769-P cells with or without RHBDF2 knockdown. (Blue: nuclei; green: nuclei of S-phase cells.) b Statistics of EDU incorporation rate (t-test). c Statistics of Cell growth speed (one-way ANOVA was used for significance test). d Cells with or without RHBDF2 knockout were used to evaluate migration ability by Transwell assay. The statistical results were shown on the right side (one-way ANONA). e Cell healing results of 786-O cells and f 769-P cells, with or without RHBDF2 knockdown at 0, 12, 24 h after scratching. g Statistics of scratching healing (two-way ANOVA). h mRNA expression of hub genes in 786-O cells and 769-P cells with or without RHBDF2 knockdown (one-way ANOVA). All the results were repeated three times, * p < 0.05, ** p < 0.01, *** p < 0.005, **** p < 0.001