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Table 1 The nanobodies studied in this paper with diagnostic application against prostate cancer

From: Nanobodies: a tool to open new horizons in diagnosis and treatment of prostate cancer

Name and type of nanobody Type of application Binding affinity (Kd) References
VHH against PSA Detection 100 nM–70 pM Saerens et al. [19]
VHH against external domain of PSMA Detection 10 nM Evazalipour et al. [8]
VHH against external domain of PSMA Detection 35 nM Zare et al. [1]
A radiolabeled (technetium-99 m) nanobody against PSMA Imaging 36 nM Evazalipour et al. [4]
technetium-99 m anti-PSMA nanobody Imaging 4 nM Evazalipour et al. [4]
111In-radiolabeled anti-PSMA nanobody Imaging N/A Kristell and Chatalic [20]
Nanobody against PSA (cAbPSA-N7) Biosensor 70 pM Huang et al. [21]
Nanobody against PSA (cAbPSA-C23) Biosensor 80 pM Huang et al. [21]
Nanobodies against PSA Biosensor 1 nM Saerens et al. [5]
Nanobodies against PSA Biosensor 100 pM–10 nM Liu et al. [6]