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Table 3 Highly connected predicted kinases in the protein–protein interaction in the STRING database

From: Quantitative phosphoproteomic analysis reveals chemoresistance-related proteins and signaling pathways induced by rhIL-6 in human osteosarcoma cells

Node kinase

UniProt ID

Protein name

Gene name

RAC-alpha serine/threonine-protein kinase (eleven connected)

O15264

Mitogen-activated protein kinase 13

MAPK13

Q15759

Mitogen-activated protein kinase 11

MAPK11

P53778

Mitogen-activated protein kinase 12

MAPK12

Q14157

Mitogen-activated protein kinase 14

MAPK14

P78527

DNA-dependent protein kinase catalytic subunit

PRKDC

P68400

Casein kinase II subunit alpha

CSNK2A1

P49840

Glycogen synthase kinase-3 alpha

GSK3A

P49841

Glycogen synthase kinase-3 beta

GSK3B

P06493

Cyclin-dependent kinase 1

CDK1

Q00535

Cyclin-dependent-like kinase 5

CDK5

P05771

Protein kinase C beta type

PRKCB

Glycogen synthase kinase-3 beta (ten connected)

P05771

Protein kinase C beta type

PRKCB

P17252

Protein kinase C alpha type

PRKCA

P31749

RAC-alpha serine/threonine-protein kinase Anillin

AKT1

Q15418

Ribosomal protein S6 kinase alpha-1

RPS6KA1

O43663

DNA-dependent protein kinase catalytic subunit

PRKDC

P49840

Glycogen synthase kinase-3 alpha

GSK3A

Q00535

Cyclin-dependent-like kinase 5

CDK5

P22694

cAMP-dependent protein kinase catalytic subunit beta

PRKACB

P22612

cAMP-dependent protein kinase catalytic subunit gamma

PRKACG

P48729

Casein kinase I isoform alpha

CSNK1A1

Mitogen-activated protein kinase 14 (nine connected)

Q15759

Mitogen-activated protein kinase 11

MAPK11

P53778

Mitogen-activated protein kinase 12

MAPK12

O15264

Mitogen-activated protein kinase 13

MAPK13

Q15418

Ribosomal protein S6 kinase alpha-1

RPS6KA1

Q15349

Ribosomal protein S6 kinase alpha-2

RPS6KA2

P51812

Ribosomal protein S6 kinase alpha-3

RPS6KA3

P31749

RAC-alpha serine/threonine-protein kinase

AKT1

P68400

Casein kinase II subunit alpha

CSNK2A1

Q13976

cGMP-dependent protein kinase 1

PRKG1