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Fig. 4 | Cancer Cell International

Fig. 4

From: Stabilization of UCA1 by N6-methyladenosine RNA methylation modification promotes colorectal cancer progression

Fig. 4

Re-expression of m6A writer restores the expression of UCA1 in KO cells. A–D Re-expression of METTL3 in KO cells restores UCA1 RNA level. A and C the representative western blot showing re-expression of METTL3 in HCT-116 KO clone#13 and DLD-1 KO clone#11. B and D the RNA level of UCA1 was detected by qRT-PCR. E–H Re-expression of WTAP in KO cells rescues UCA1 RNA level. E and G the representative western blot showing re-expression of WTAP in HCT-116 KO clone#28 and DLD-1 KO clone#37. F and H the RNA level of UCA1 was detected by qRT-PCR. Error bars represent SD, n = 3, *P < 0.05, **P < 0.01, ***P < 0.005

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