Table 1 The expression of SNHG4 and its clinical significance in a variety of diseases

Gastric cancer (GC)

53 tissue samples from GC patients

Upregulation

Lymph node metastasis, tumour invasion, TNM stage

1.54

P < 0.001

Poor

Oncogene

33236157

Renal cell carcinoma (RCC)

99 pairs of RCC tissues and adjacent normal tissues

Upregulation

Advanced T stage, node invasion, distant metastasis status, poor tumour grade, relapse status

1.50

P = 0.007

Poor

Oncogene

33088220

Glioblastoma (GBM)

62 pairs of GBM tissues and adjacent normal tissues

Upregulation

–

3.32

–

Poor

Oncogene

32427712

Neuroblastoma

30 pairs of neuroblastoma tissues and adjacent normal tissues

Upregulation

–

–

P = 0.018

Poor

Oncogene

32614236

Prostate cancer (PCa)

113 pairs of PC tissues and adjacent normal tissues

Upregulation

Tumour stage, lymph node metastasis

–

P = 0.005

Poor

Oncogene

31608997

Colorectal cancer (CRC)

12 pairs of CRC tissues and adjacent normal tissues

Upregulation

–

–

–

–

Oncogene

33744866

Osteosarcoma

24 pairs of osteosarcoma tissues and adjacent normal tissues

Upregulation

Distant metastasis, lager tumour size, advanced pathological stage

–

P = 0.047

Poor

Oncogene

32537941

136 cases of osteosarcoma patients and 40 adjacent normal tissue

Upregulation

Tumour size

–

P = 0.001

Poor

Oncogene

30152090

Cervical cancer (CC)

27 pairs of CC tissues and adjacent normal tissues

Upregulation

–

–

–

–

Oncogene

31590627

Liver cancer

371 liver cancer tissues and 50 normal liver tissues

Upregulation

Histological type, histologic grade, stage, T classification, survival status

–

P < 0.001

Poor

Oncogene

31967298

Hepatocellular carcinoma (HCC)

49 pairs of HCC tissues and adjacent normal tissues

Upregulation

–

–

P < 0.001

Poor

Oncogene

30537372

Non-small-cell lung cancer (NSCLC)

50 pairs of NSCLC tissues and adjacent normal tissues

Upregulation

–

–

–

Poor

Oncogene

33816782

Neonatal pneumonia (NP)

15 peripheral venous blood from NP patients and healthy controls

Downregulation

–

–

–

–

–

34450538

Diabetic retinopathy (DR)

60 tissue samples from DR patients, diabetic patients without complication and healthy controls

Downregulation

–

–

–

–

–

32454787

Acute cerebral infarction (ACI)

30 tissue samples from ACI patients and healthy controls

Downregulation

–

–

–

–

–

32982175

Acute myeloid leukaemia (AML)

60 tissue samples from AML patients and healthy controls

Downregulation

–

–

–

–

–

32319862

Endometriosis

25 EC samples and EU samples

Upregulation

–

–

–

–

–

32525017