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Fig. 4 | Cancer Cell International

Fig. 4

From: CircRFX3 contributes to glioma progression through the circRFX3-miR-1179/miR-1229-VASP axis

Fig. 4

CircRFX3 silencing suppressed glioma cell progression by regulating miR-1179 and miR-1229. A The expression level of miR-1179 in A172 and U251 cells transfected with anti-miR-1179 or anti-NC was examined via qRT-PCR analysis. B The expression level of miR-1229 in A172 and U251 cells transfected with anti-miR-1229 or anti-NC was examined via qRT-PCR analysis. C–G After the transfection of sh-NC, sh-circRFX3#1, sh-circRFX3#1 + anti-NC, sh-circRFX3#1 + anti-miR-1179 or sh-circRFX3#1 + anti-miR-1229, the C viability, D colony formation, E and F migration and invasion, and G apoptosis of A172 and U251 cells were evaluated by CCK-8 assay, colony formation assay, transwell assay and flow cytometry analysis, respectively. *P < 0.05, **P < 0.01

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