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Table 2 Univariate analysis to assess the association of clinicopathological parameters with prognosis of HPC

From: Serum-derived exosomes promote CD8+ T cells to overexpress PD-1, affecting the prognosis of hypopharyngeal carcinoma

Parameter

OS

DFS

Hazard ratio (95% CI)

P-value (Cox)

Hazard ratio (95% CI)

P-value (Cox)

PD-1 CD8+ T cell

9.664 (1.299 ~ 71.899)

0.027*

5.447 (1.269 ~ 23.371)

0.023*

Sex

22.567 (0.016 ~ 32,759)

0.401

1.847 (0.248 ~ 13.672)

0.551

Age

2.410 (0.943 ~ 6.161)

0.066

1.141 (0.511 ~ 2.549)

0.748

Differentiation

2.342 (0.930 ~ 5.897)

0.071

2.899 (1.163 ~ 7.222)

0.022*

Tumor size

1.139 (0.502 ~ 2.586)

0.755

1.306 (0.585 ~ 2.916)

0.515

Clinical stage

5.203 (1.221 ~ 22.168)

0.026*

3.973 (1.189 ~ 13.273)

0.025*

Lymph node metastasis

4.492 (1.534 ~ 13.155)

0.031*

2.559 (1.077 ~ 6.077)

0.033*

  1. DFS: disease-free survival; OS: overall survival
  2. P values in bold denote significance at < 0.05 level