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Fig. 3 | Cancer Cell International

Fig. 3

From: Model constructions of chemosensitivity and prognosis of high grade serous ovarian cancer based on evaluation of immune microenvironment and immune response

Fig. 3

Tumor-infiltrating immunocytes and immune functional features of the cohorts. a Immune characteristic heat maps of TCGA + GTEx cohort(left) and GEO cohort (right). TCGA: n = 321, GTEx: n = 88, GEO: n = 296 (cancer: 270, normal: 26). Tumor purity, ESTIMATE total score, immune cell score, stroma score, immune infiltrating cells, immune function and pathway activity of every single sample are annotated by color depth. b Comparation of immune infiltrating cells between normal ovarian epithelium samples (green) and HGSOC samples (yellow) in TCGA + GTEx cohort (left) and GEO cohort (right). The Boxes horizontal line represents the median value, and the top line and bottom line represent the 25th and 75th percentiles (interquartile range). The whiskers encompass 1.5 times the interquartile range. The differences were analyzed by Wilcoxon signed rank test (*, P < 0.05; **, P < 0.01; ***, P < 0.0001). c Comparations of immune functions and pathway activities between normal ovarian epithelium samples (green) and HGSOC samples (yellow) in TCGA + GTEx cohort (left) and GEO cohort (right), and the annotation is same as b

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