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Fig. 6 | Cancer Cell International

Fig. 6

From: NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth

Fig. 6

Transfecting HDGF restores the cell proliferation in NAP1L1-suppressing breast cancer cells through c-Jun/CCND1 signal. A NAP1L1, HDGF, c-Jun, and CCND1 protein levels were evaluated in NC, shNAP1L1, and HDGF-shNAP1L1 breast cancer cells. B RT-qPCR data was used to measure the HDGF expression after restoring HDGF in shNAP1L1 breast cancer cells. C MTT assays indicated that transfecting HDGF restores the cell growth of breast cancer. D Transfecting HDGF restores EdU staining of breast cancer (scale bar: 200 μm). The data are presented as mean ± s.d. from three independent experiments. *P < 0.05 vs. control; **P < 0.01; ***P < 0.001

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