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Fig. 5 | Cancer Cell International

Fig. 5

From: Starvation induced autophagy promotes the progression of bladder cancer by LDHA mediated metabolic reprogramming

Fig. 5

Overexpression of LDHA Was Closely Related to Clinical BLCA Patients. a The mutation features and alteration frequency with mutation type of LDHA for TCGA tumours were demonstrated with the cBioPortal tool. b Pictures of immunohistochemical staining with CAB069404 from normal bladder or BLCA tissue showing LDHA protein expression in uroepithelial squamous epithelial cells. c. Real-time qPCR was used to determine the expression of LDHA mRNA in cancer and adjacent tissues (n = 15, paired Student’s t test, P** < 0.01). d Western blotting was performed to determine the expression of LDHA proteins in cancer and adjacent tissues, which were randomly selected from eight paired clinical samples. e Expression of LDHA in 60 BLCA patients with different depths of infiltration sourced from Oncomine. f The transcriptional expression relationship between LDHA and ATG5 in 378 BLCA tissues was analysed by Pearson correlation (r = 0.6107, P < 0.001)

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