Fig. 3
From: CEBPG promotes acute myeloid leukemia progression by enhancing EIF4EBP1
a Volcano Plot of RNA-seq results for NB4 cell line in either the absence or presence of CEBPG. b Volcano Plot of RNA-seq results for MV4-11 cell line in either the absence or presence of CEBPG. c Top 10 downregulated and top 10 upregulated genes upon CEBPG knockdown in NB4 cell line. d Top 10 downregulated and top 10 upregulated genes upon CEBPG knockdown in MV4-11 cell line. e Enrichment analysis results of all DEGs by using the KEGG Pathway Database. f qRT-PCR results of 6 genes (EIF4EBP1, PLCG1, EIF4E, AXL, PIK3R2 and MET) from EGFR tyrosine kinase inhibitor resistance signaling pathway in NB4 cell line when silencing CEBPG. g qRT-PCR results of 2 genes (PDGFB and SRC) from EGFR tyrosine kinase inhibitor resistance signaling pathway in NB4 cell line when silencing CEBPG. h ChIP-Seq data of AML cell lines and K562 cell line showed that the promoter region of EIF4EBP1 had coincident H3K27ac signals (tracks 1–6), ChIP-Seq data of K562 cell line further indicated that EIF4EBP1 was bound by CEBPG at its TSS-proximal regions (track 7)