Fig. 7

The correlations of iCAFs scores with gene mutation, molecular subtype and ICB responsiveness. A, B The iCAFs score was negatively correlated with the mutation frequency of FGFR3. C iCAFs score was significantly upregulated in BLCA with stromal rich molecular subtype. D The TIDE algorithm indicated significantly lower responsiveness in high iCAFs patients, possibly due to the dysfunction and exclusion of T cells. *** p < 0.001, ns: not significant