Fig. 4

Construction of the survival model in the TCGA-LIHC dataset: A 182 differentially expressed genes between IC1/IC3 and IC2 were imported into the univariate analysis workflow of the Cox proportional hazard model and finally twenty-seven genes with P < 0.05 were accessed. B Twenty-seven genes with log-rank P < 0.05 in Cox univariate hazard analysis shown in Fig. 4A were selected out for cox multivariate hazard analysis and finally we got seven genes with P < 0.05 in Cox multivariate hazard analysis. C The KM curve in high-risk and low-risk groups. D ROC curve analysis at 24, 36, and 60 months. E The KM curve and ROC curve analysis of TNM stage in TCGA-LIHC database. F, The SNV score in different risk groups (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, ns means no statistical significance, with a Wilcox test)