Fig. 2

Overexpression of mir-30b-5p inhibited PTC cell proliferation and promotes apoptosis. A The relative expression level of mir-30b-5p was significantly up-regulated by mir-30b-5p mimic. B Cell proliferation was detected in both PTC cells after transfection of mir-30b-5p mimic by CCK8 kit. C Representative images of EdU assay. D Q1, Q2, Q3 and Q4 zones represent necrosis, late apoptosis, early apoptosis and healthy cells, respectively. E The relative fold changes of EdU positive cells were detected mir-30b-5p mimic. F The relative fold changes of apoptosis-positive cells were detected mir-30b-5p mimic. Data are presented as the mean ± SD (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001)