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Fig. 5 | Cancer Cell International

Fig. 5

From: Distinct associations of NEDD4L expression with genetic abnormalities and prognosis in acute myeloid leukemia

Fig. 5

Biological insights of aberrant NEDD4L in AML. a Expression heatmap of differentially expressed genes between NEDD4L overexpression and underexpression groups in AML (|log2 FC|> 1.5, FDR < 0.05 and P < 0.05). b Volcano plot of differentially expressed genes between NEDD4L overexpression and underexpression groups in AML. c Gene Ontology analysis of differentially expressed genes conducted using online website of STRING (http://string-db.org). d Expression heatmap of differentially expressed microRNAs between NEDD4L overexpression and underexpression groups in AML. e Venn results of microRNAs which could target NEDD4L predicted by miRDB (http://mirdb.org/miRDB/), TargetScan (http://www.targetscan.org/vert_72/), starBase (http://starbase.sysu.edu.cn/) and miRWalk (http://mirwalk.umm.uni-heidelberg.de/)

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