Fig. 3
From: PESV represses non-small cell lung cancer cell malignancy through circ_0016760 under hypoxia
Circ_0016760 overexpression attenuated the impacts of PESV treatment on NSCLC cell processes under hypoxia. A The overexpression efficiency of circ_0016760 was detected by qRT-PCR in A549 and H1299 cells. B The effects between PESV treatment and circ_0016760 overexpression on circ_0016760 expression under hypoxia were determined by qRT-PCR in A549 and H1299 cells. C, D Transwell assay was conducted to determine the influences between PESV treatment and circ_0016760 overexpression on the migration and invasion of A549 and H1299 cells under hypoxia. E, F Cell colony formation and MTT assays were carried out to unveil the influences between PESV treatment and enforced circ_0016760 expression on cell proliferation under hypoxia in A549 and H1299 cells. G Western blot analysis was carried out to determine the influences between PESV treatment and circ_0016760 overexpression on PCNA protein expression under hypoxia. H Tube formation assay was conducted to determine the influences between PESV treatment and circ_0016760 overexpression on tube formation under hypoxia. *P < 0.05