Fig. 2From: The high methylation level of a novel 151-bp CpG island in the ESR1 gene promoter is associated with a poor breast cancer prognosisMethylation levels at the ESR1 CpG island among Mexican BC patients. A The methylation levels were significantly lower in ERα+ than in controls or ERα− samples (*p < 0.05). B ESR1 transcript levels. Relative ESR1 mRNA amount was determined by qRT-PCR and normalized with 18S RNA gene expression. Data represented the mean ± SD of three independent experiments (**p < 0.05)Back to article page