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Table 2 Diagnostic performances of studied testing for ECA patients

From: HPV E6/E7 mRNA in situ hybridization in endocervical adenocarcinoma: implications for prognosis and diagnosis

HPVA vs. NHPVA

AUC

95%CI

Sensitivity

Specificity

P16 IHC

0.751

0.620–0.882

0.602

0.900

HPV DNA

0.802

0.653–0.951

0.805

0.800

HPV genotype

0.566

0.379–0.754

0.633

0.500

HPV RNAscope

0.799

0.629–0.929

0.758

0.800

  1. AUC, area under curve; 95%CI, 95% confident interval; HPVA, HPV-associated adenocarcinoma; NHPVA, nonHPV-associated adenocarcinoma; IHC, immunohistochemistry; HPV RNAscope