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Table 2 Diagnostic performances of studied testing for ECA patients

From: HPV E6/E7 mRNA in situ hybridization in endocervical adenocarcinoma: implications for prognosis and diagnosis

HPVA vs. NHPVA AUC 95%CI Sensitivity Specificity
P16 IHC 0.751 0.620–0.882 0.602 0.900
HPV DNA 0.802 0.653–0.951 0.805 0.800
HPV genotype 0.566 0.379–0.754 0.633 0.500
HPV RNAscope 0.799 0.629–0.929 0.758 0.800
  1. AUC, area under curve; 95%CI, 95% confident interval; HPVA, HPV-associated adenocarcinoma; NHPVA, nonHPV-associated adenocarcinoma; IHC, immunohistochemistry; HPV RNAscope