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Fig. 7 | Cancer Cell International

Fig. 7

From: The circular RNA circSLC7A11 functions as a mir-330-3p sponge to accelerate hepatocellular carcinoma progression by regulating cyclin-dependent kinase 1 expression

Fig. 7

CircSLC7A11 accelerated HCC progression through the circSLC7A11/miR-330-3p/CDK1 axis. a, b Relative mRNA and protein levels of CDK1 in HCCLM3 and Hep3B cells transfected with si-circ, oe-circ, mimics, inhibitor, or negative control, detected by Western blotting and qRT-PCR. c–e CCK-8, colony formation, and EdU assays detected proliferation in HCCLM3 and Hep3B cells transfected with si-circ, oe-circ, mimics, inhibitor, or negative control. Scale bar, 100 μm. f Cell migration detected by wound-healing assay in HCCLM3, and Hep3B cells transfected with si-circ, oe-circ, mimics, inhibitor, or negative control. Scale bar, 200 μm. Data are means ± SD (ns = not significant, *p < 0.05; **p < 0.01; ***p < 0.001)

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Cancer Cell International

ISSN: 1475-2867

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