Skip to main content
Fig. 8 | Cancer Cell International

Fig. 8

From: The circular RNA circSLC7A11 functions as a mir-330-3p sponge to accelerate hepatocellular carcinoma progression by regulating cyclin-dependent kinase 1 expression

Fig. 8

CircSLC7A11 knockdown inhibited HCC progression and metastasis in vivo. a Image of subcutaneous tumor tissues in the sh-circSLC7A11 and sh-NC groups (n = 6). b Relative tumor weights (n = 6). c Tumor volume was measured weekly (n = 6). d Relative expression levels of circSLC7A11, miR-330-3p, and CDK1 mRNA in subcutaneous tumor tissues, detected by qRT-PCR. e Relative expression levels of CDK1, cyclin B1, E-cadherin, and N-cadherin in subcutaneous tumor tissues, detected by Western blotting. GAPDH was used as a negative control. f Relative expression levels of CDK1, cyclin B1, E-cadherin, N-cadherin, and Ki-67 in subcutaneous tumor tissues, detected by immunohistochemical (IHC) analysis. g Image of lung metastasis in the sh-circSLC7A11 and sh-NC groups. Representative images of hematoxylin and eosin (H&E) staining of lung metastasis in HCCLM3 cells. Scale bar, 100 μm. Data are means ± SD (*p < 0.05; **p < 0.01)

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us